Lorazepam

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Lorazepam

More commonly known by the brand names Ativan and Loreev, lorazepam was first synthesised in 1963 by Wyeth Pharmaceuticals. It has been available in the UK since 1972 and is classified as a benzodiazepine due to its anxiolytic, hypnotic, sedative, anticonvulsant and muscle relaxant effects. It is available in lorazepam 3mg hard tablets and has been commonly prescribed in the UK since its license and approval.

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What is Lorazepam Used for?

Lorazepam is prescribed in the UK primarily to address anxiety disorders - a group of mental health conditions characterized by excessive worry, apprehension or fear. Different types of anxiety include social anxiety, generalized anxiety disorder (GAD), phobias, panic disorder, obsessive-compulsive disorder (OCD) and post-traumatic stress disorder (PTSD).

They can be caused by many factors including stress, trauma, personality traits, hormonal imbalances and underlying medical conditions. Unease can considerably affect the quality of life of sufferers. It may result in social isolation, depression, sleep disturbances and a decline in physical health.

Mental Health UK states that anxiety is a very common affliction. Approximately 10% of the UK population, which is roughly 8 million people, experience an anxiety disorder. The overwhelming statistics on its prevalence and the significance of its impact highlight the need for a reliable solution.

Lorazepam stands as a reliable medication for anxiety disorders. Apart from disquiet-related conditions, this medicine has proven to be effective in addressing sleep deprivation, also known as insomnia, namely if it is caused by anxious thoughts at bedtime.

The anticonvulsant and muscle relaxing properties of this drug alleviate epileptic seizures, cramps and muscle spasms.

Does Lorazepam Work?

When it comes to treating anxiety-related conditions, people often ask which drug actually works. Lorazepam has established itself as a reliable solution for anxiety, insomnia, seizures and spasms.

This medicine soothes brain activity and suppresses racing thoughts promoting calmness and sedation. People note a feeling of control over their emotions and a considerable reduction in anxiousness. Lorazepam also causes drowsiness helping people to fall asleep faster and sleep deeper. A better rest results in improved daily productivity, elevated mood and enhanced well-being.

Epileptic seizures are often caused by excessive neural activity in the brain. By soothing it, this medication reduces the frequency and severity of seizure episodes helping patients regain control over their bodies. Muscle spasms can result in pain and discomfort, fatigue and movement restriction. Lorazepam relaxes the body reducing tension, that provides relief for those who suffer from cramps.

By addressing multiple mental and physical conditions at the same time, this versatile medicine considerably improves the quality of life of patients. It allows people to reclaim control over their minds, emotions and bodies, have restorative sleep and live life to the fullest.

How Does Lorazepam Work?

Like other benzodiazepines, lorazepam works by increasing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) - the major inhibitory neurotransmitter in the CNS. It interacts selectively with GABA-A receptors - ion channels through which chloride ions are permitted to enter the neuron once GABA binds to them.

Lorazepam interacts with a different site on the GABA-A receptor, enhancing the receptor’s ability to bind with GABA. It leads to the better opening of the ion channel through which chloride ions enter the neuron.

The entry of chloride ions makes the neuronal membrane less likely to fire and, therefore, lowers the excitability of neurons. In this way, lorazepam produces a variety of actions such as sedation, anxiolytic effect, muscle relaxation and anticonvulsant activity.

Lorazepam has a relatively fast onset of action; it kicks in within 15-30 minutes, depending on individual factors like metabolism and whether or not it was consumed with food. Its duration of action also depends on the personal metabolism rate and ranges from 6 to 8 hours.

Lorazepam Dosage Instructions

In order to ensure safe and effective treatment with lorazepam, it is vital to follow the dosage instructions. They can be provided by a healthcare practitioner or found printed on the patient information leaflet.

Lorazepam dose typically depends on different variables such as the treated issue, age and pre-existing medical conditions. It is important to stay in touch with a doctor throughout the whole treatment process. The dosage can be altered by a general practitioner or a consulting physician based on its effectiveness and experienced side effects.

It is recommended to stick with the scheduled routine consistently and take a dose a few times a day as prescribed to maintain the required concentration of the substance in the bloodstream. If you missed a dose, take it as soon as possible. If it is almost time for the next intake, skip it and adhere to the schedule. Do not double the next dosage to make up for the missed one, taking too much may cause an adverse reaction.

Take a pill with a full glass of water, with or without food. Ingesting this drug with a fatty meal can delay its onset of action. The maximum dosage for lorazepam is 10mg per day. Exceeding it may result in increased exposure to side effects and is not recommended.

Lorazepam has the potential to develop tolerance and dependency, namely if the dosage instructions are not strictly followed or if this medicine is taken for too long. Taking it for longer than 4 weeks is not advised unless instructed by a healthcare professional.

This medication can cause withdrawal syndrome if abruptly discontinued. It is advisable to taper the dose off gradually until it is no longer needed.

Is Lorazepam a Safe Choice?

Lorazepam is a safe medicine when taken in accordance with instructions and precautions. Prior to being licensed, medications undergo a thorough evaluation process. They need to meet the stringent standards for safety and efficacy set by regulatory authorities.

Food and Drug Administration (FDA) is a regulatory body that is responsible for promoting public health. It assesses and tests medicines, food, vaccines and other consumer products before they are sold to people. Lorazepam has been licensed and approved by the FDA as a safe and effective treatment for anxiety-related conditions.

Even though safe, this medication can exacerbate certain medical conditions and is contraindicated for some people. Breastfeeding/pregnant women and patients with acute narrow-angle glaucoma, severe respiratory insufficiency and sleep apnoea syndrome should avoid lorazepam. Allergy/hypersensitivity to the drug, severe liver disease and myasthenia gravis also comprise the list of contraindications.

This medicine can interact with certain medications and substances resulting in potentially dangerous complications. It is not recommended to mix it with antidepressants, muscle relaxants, anticonvulsants and CNS depressants including alcohol and opioids.

Before you buy lorazepam, it is advisable to discuss this treatment with a healthcare practitioner. The specialist will assess your health, evaluate the concurrent medications and determine if the benefits of the drug outweigh the risks.

Side Effects of Lorazepam

Treatment with lorazepam may be associated with certain side effects. Even though they are mostly mild and manageable and now everyone will experience them, it is recommended to be aware of them. Common adverse reactions include fatigue, confusion, headaches, dizziness/vertigo, sleepiness, nausea and dry mouth.

It is advised to stay adequately hydrated to alleviate headaches and dry mouth. Taking lorazepam with a snack or a light meal can prevent stomach upset. Avoid activities that require full attention like driving or machinery operating while experiencing dizziness or drowsiness. Respiratory depression, allergic reactions, mood changes and memory problems occur extremely rarely.

If side effects persist or get bothersome, it is recommended to consult with a GP. The specialist can adjust the dosage of lorazepam to reduce the severity of adverse reactions and provide tips on how to manage them.

Reviews of Lorazepam

We encourage our clients who buy lorazepam or any other product from us to leave a review. Reviews are an indispensable tool for any reputable online platform. By giving customers a voice, it allows them to express their opinions by highlighting the pros and cons of lorazepam or other medications and services.

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Where to Buy Lorazepam in the UK

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They are not limited by space and sell a wider variety of different medications including lorazepam. With e-drugstores, people can conveniently compare products and choose the best options. The prices online are usually lower which makes purchases more beneficial. Bulk buying option and promotions allows for greater savings. The bigger the order - the better the deal.

There is no need to go to a doctor for a prescription or wait in lines to buy medicine anymore. No more face-to-face interactions with healthcare practitioners. All products are conveniently ordered without a prescription and discreetly delivered to the doorstep within a short period.

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Good online pharmacies prioritize the confidentiality of their clients and provide only secure payment methods like Visa or MasterCard. Legitimate and easily accessible contact details are also a sign of a trustworthy platform. Call or live chat the platform in real time to establish a line of communication.

Buy Lorazepam for Anxiety Online

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Last Reviewed: 05th November 2024
Next Review Due: December 2025

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